2019 Journal Club Schedule
Speaker | Institute | Title | Host/Sponsor | |
---|---|---|---|---|
1/25/2019 | Smita Joshi, PhD | "Thrombocytopenia-associated mutations in Ser/Thr kinase MASTL deregulate actin cytoskeletal dynamics in platelets" | ||
2/22/2019 | Shravani Kanakanagavalli | "Glucose metabolism and metabolic flexibility in blood platelets" |
2018 Journal Club Schedule
2017 Journal Club Schedule
2015 Journal Club Schedule
Spring 2014
DATE | PRESENTER | TITLE |
---|---|---|
1/24/2014 | Deepa Jonnalagadda | "Biogenesis of the demarcation membrane system (DMS) in megakaryocytes" |
2/28/2014 | Mennakshi Banerjee | "ADAP interactions with talin and kindlin promote platelet integrin aIIbb3 activation and stable fibrinogen binding" |
3/28/2014 | Smita Joshi | |
4/25/2014 | ||
5/23/2014 | Travis Sexton |
Fall 2013
DATE | PRESENTER | TITLE |
---|---|---|
8/23/2013 | Binggang Xiang, PhD | Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice |
9/27/2013 | Zhenyu Li, PhD | |
10/25/2013 | Yuri Klyachkin, PhD | Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2 |
11/15/2013 | Meenakshi Banerjee | Clot retraction is mediated by factor XIII-dependent fibrin-αIIbβ3-myosin axis in platelet sphingomyelin-rich membrane rafts |
12/13/2013 | Yunjie Huang | A directional switch of integrin signalling and a new anti-thrombotic strategy |
Spring 2013
DATE | PRESENTER | TITLE |
---|---|---|
1/25/2013 | Susan S. Smyth, MD, PhD | |
2/22/2013 | Shaojing Ye, PhD | The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes |
3/22/2013 | Paul Mueller | |
4/19/2013 | Travis Sexton, PhD | Platelets activated during myocardial infarction release functional miRNA which can be taken up by endothelial cells and regulate ICAM1 expression |
5/24/2013 | Smita Joshi | The VPS33B-binding protein VPS16B is required in megakaryocyte and platelet a-granule biogenesis |
6/28/2013 | Summer Vacation | Summer Vacation |
7/26/2013 | Summer Vacation | Summer Vacation |
Fall 2012
DATE | PRESENTER | TITLE |
---|---|---|
8/24/2012 | Summer Vacation | Summer Vacation |
9/28/2012 | Zhenyu Li, PhD | Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury |
10/26/2012 | Fanmuyi Yang, PhD | Protein disulfide isomerase inhibitors constitute a new class of antithrombotic agents |
11/16/2012 | Yuri Klyachkin, PhD | Protein Kinase C εExpression in Platelets from Patients with Acute Myocardial Infarction |
12/13/13 | Yunjie Huang |
Spring 2012
DATE | PRESENTER | TITLE |
---|---|---|
01/27/2012 | Prof. Susan S. Smyth | Thrombin-Receptor Antagonist Vorapaxar in Acute Coronary Syndromes |
02/24/2012 | Meenakshi Banerjee | Platelet Microparticles Promote Neural Stem Cell Proliferation, Survival and Differentiation |
03/23/2012 | Yunjie Huang | Polycomb group ring finger 1 cooperates with Runx1 in regulating differentiation and self-renewal of hematopoietic cells |
04/27/2012 | Paul Mueller | The macrophage mannose receptor promotes uptake of ADAMTS13 by dendritic cells |
5/25/2012 | Prof. Sidney W. Whiteheart | Platelets and platelet-like particles mediate intercellular RNA transfer |
6/22/2012 | Jinchao Zhang | Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer |
7/27/2012 | Summer Vacation | Summer Vacation |
8/24/2012 | Summer Vacation | Summer Vacation |
Fall 2011
DATE | PRESENTER | TITLE |
---|---|---|
8/26/2011 | Summer Vacation | |
9/23/2011 | Dr. Binggang Xiang | Connexin 37 limits thrombus propensity by downregulating platelet reactivity |
10/28/2011 | Meenakshi Banerjee | Histones induce rapid and profound thrombocytopenia in mice |
11/18/2011 | Jinchao Zhang | Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis |
12/23/2011 | Christmas Vacation |
Spring 2011
DATE | PRESENTER | TITLE |
---|---|---|
01/28/2011 | Prof. Susan S. Smyth | Hyperglycemia-Induced Cerebral Hematoma Expansion is Mediated by Plasma Kallikrein |
02/25/2011 | Prof. Sidney W. Whiteheart | |
03/25/2011 | Dr. Tao Wu | Identification of an Antithrombotic Allosteric Modulator that Acts Through Helix 8 of PAR1 |
04/22/2011 | Deepa Jonnalagadda | TBA |
5/27/2011 | Yunjie Huang | Down-Regulation of Stathmin Expression is Required for Megakaryocyte Maturation |
6/24/2011 | Lorenzo Frederico | Platelet gene therapy improves hemostatic function for integrin αIIbβ3-deficient dogs |
7/22/2011 | Summer Vacation | |
8/26/2011 | Summer Vacation |
Fall 2010
DATE | PRESENTER | TITLE |
---|---|---|
9/24/2010 | Dr. Michael Chicka | The platelet interior revisited: electron tomography reveals tubular a-granule subtypes. |
10/29/2010 | Lorenzo Federico | Extracellular DNA traps promote thrombosis |
11/19/2010 | Shaojing Ye | Infusion of mature megakaryocytes into mice yields functional platelets |
12/24/2010 | 12/24/2010CHRISTMAS VACATION |
Spring 2010
DATE | PRESENTER | TITLE |
---|---|---|
1/22/2010 | Zachary Fulkerson/ Abelghaffar K Salous | CIB1 Regulates Endothelial Cells and Ischemia-Induced Pathological and Adaptive Angiogenesis |
2/26/2010 | Dr. Sydney Whiteheart | Platelets amplify inflammation in arthritis via collagen-dependent microparticle production |
3/26/2010 | Dr. Susan Smyth | Platelets Play an Essential Role in Separating the Blood and Lymphatic Vasculatures During Embryonic Angiogenesis |
4/30/2010 | Zachary Fulkerson | G Protein Subunit Ga13 Binds to Integrin aIIbB3 and Mediates Integrin "Outside-In" Signaling |
5/28/2010 | Dr. Tao Wu | Platelet JNK1 is involved in secretion and thrombus formation |
6/25/2010 | Dr. Zhenyu Li | The AMP-activated kinase (AMPK) alpha2 subunit is involved in platelet signaling, clot retraction and thrombus stability. |
7/31/2010 | SUMMER VACATION | |
8/28/2010 | SUMMER VACATION |
Fall 2009
DATE | PRESENTER | TITLE |
---|---|---|
9/25 | Zachary Fulkerson | |
10/30 | Rania Al Hawas | |
11/20 | Abdelghaffar K. Salous |
Spring 2009
DATE | PRESENTER | TITLE |
---|---|---|
1/30 | Fanmuyi Yang | Endothelial Cell PECAM Promotes Atherosclerosis Lesions in Areas of Disturbed Flow in ApoE-Deficient Mice. |
2/27 | Wangsun Choi | |
3/27 | Shaojing Ye | The Tyrosine Phosphatase CD148 is an Essential Positive Regulator of Platelet Activation and Thrombosis. |
4/24 | Zhenyu Li | Loss of pleckstrin defines a novel pathway for PKC-mediated exocytosis. |
5/29 | Samy M. Selim | Platelet Matrix Metalloprotease-1 Mediates Thrombogenesis by Activating PAR1 at a Cryptic Ligand Site |
6/26 | Michael Chicka | |
7/31 | No Journal Club-Summer Vacation | |
8/28 | No Journal Club-Summer Vacation |
Fall 2008
DATE | PRESENTER | TITLE |
---|---|---|
9/26 | Zach Fulkerson (Smyth Lab) | Genetic Components of the Circulation Clock Regulate Thrombogenesis in Vivo |
10/31 | Whiteheart Lab | |
11/28 | Anping Dong (Smyth Lab) |
Spring 2008
DATE | PRESENTER | TITLE |
---|---|---|
1/28 | Zubair Ahmad Karim | |
2/25 | Julie Oestreich | Influence of Omeprazole on the Antiplatelet Action of Clopidogrel Associated with Aspririn. |
3/24 | Wangsun Choi | Identification of a Fibril-Independent Platelet Contractile Mechanism Regulating Primary Hemostasis and Thrombus Growth. |
5/30 | Fanmuyi Yang (Smyth Lab) | In Vivo Imaging in Mice Reveals Local Cell Dynamics and Inflammation in Obese Adipose Tissue. |
6/27 | Whiteheart Lab | |
7/25 | Lorenzo Federico (Smyth Lab) | |
8/29 | Whiteheart Lab |
Fall 2007
DATE | PRESENTER | TITLE |
---|---|---|
8/27 | Susan Smyth, M.D. | The antithrombotic potential of selecive blockade of talin-dependent integrin activation. |
9/24 | Sidney W. Whiteheart, Ph.D. | Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion. |
10/22 | Qiansheng Ren | |
11/26 | Rebekah Waikel, Ph.D. | Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype. |
Spring 2007
DATE | PRESENTER | TITLE |
---|---|---|
01/22 | Zubair Karim (Whiteheart lab) | PKC-delta regulates collagen-induced platelet aggregation through inhibition of VASP-mediated filopodia formation. |
02/26 | Qiansheng Ren (Whiteheart lab) | “Vascular wall–produced prostaglandin E2 exacerbates arterial thrombosis and atherothrombosis through platelet EP3 receptors” by Gross et al. |
03/26 | Chunxia Zhao (Whiteheart lab) | |
04/23 | TBA (Smyth lab) |
Fall 2006
DATE | PRESENTER | TITLE |
---|---|---|
07/24 | Susan Smyth, MD | Platelet-Derived Serotonin Mediates Liver Regeneration |
08/28 | Sidney Whiteheart, PhD | Rac1 is Essential for Platelet Lamelllipodia Formation and Aggregate Stability Under Flow |
9/25 | Scott Akers, PharmD | The active metabolite of Clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts |
10/23 | Garland Crawford (Whiteheart lab) | Identification of a Two-Stage Platelet Aggregation Process Mediating Shear-Dependent Thrombus Formation |
11/27 | Julie Oestreich (Akers lab) | |
12/25 | No BCJC - Holiday |