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Joseph B. Zwischenberger, M.D.
jzwis2's picture
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joseph.zwischenberger@uky.edu
859-323-6013
MN-264 Medical Science Bldg, 800 Rose St, Lexington, KY 40536-0298
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Position(s): 
Professor of Surgery
Professor of Pediatrics
Affiliation(s): 
Surgery
Cardiovascular Research Center
Other Affiliation(s): 
Surgery/Cardiothoracic
Department Staff
MD/PhD Program Mentor
CVRC - Affiliated Faculty
Interests / Specialties: 
Oxygenation and CO2 removal during acute respiratory failure
Severe respiratory failure unresponsive to conventional medical management
Multiple modality treatment of resectable esophageal cancer
Physiology of cardiopulmonary bypass (CPB)
Perfusion-induced systemic hyperthermia for advanced lung cancer
Bio / Education: 

Medical School
University of Kentucky

Residency
University of Michigan
Ann Arbor, Michigan

Fellowships
Cardiac Division, NIH
Cardiothoracic Surgery, University of Michigan
Critical Care, University of Michigan

Certification
American Board of General Surgery
American Board of General Surgery - Vascular Surgery
American Board of Thoracic Surgery

Listen to an interview with Zwisch on his progress with the artificial lung.

PubMed Publications: 
  • Lamb, M ; Bazan, VM ; Jax, MD ; Zwischenberger, JB ; Meyerson, SL "Repair of Pulmonary Vascular Injury: A Take-Home Low Fidelity Simulator." The Annals of thoracic surgery (2021): [PubMed Link] | [ Full text ]
  • Gupta, M.; Dugan, A.; Chacon, E ; Davenport, DL ; Shah, MB ; Marti, F.; Roth, JS ; Bernard, A.; Zwischenberger, JB ; Gedaly, R. "Detailed perioperative risk among patients with extreme obesity undergoing nonbariatric general surgery." Surgery 168, 3 (2020): 462-470. [PubMed Link] | [ Full text ]
  • Bohnen, JD ; George, BC ; Zwischenberger, JB ; Kendrick, DE ; Meyerson, SL ; Schuller, MC ; Fryer, JP ; Dunnington, GL ; Petrusa, ER ; Gee, DW "Trainee Autonomy in Minimally Invasive General Surgery in the United States: Establishing a National Benchmark." Journal of surgical education 77, 6 (2020): e52-e62. [PubMed Link] | [ Full text ]
  • Rajagopal, K.; Keller, SP ; Akkanti, B ; Bime, C ; Loyalka, P ; Cheema, FH ; Zwischenberger, JB ; Banayosy, El ; Pappalardo, F.; Slaughter, MS ; Slepian, MJ "Advanced Pulmonary and Cardiac Support of COVID-19 Patients: Emerging Recommendations From ASAIO-A "Living Working Document"." ASAIO journal (American Society for Artificial Internal Organs : 1992) 66, 6 (2020): 588-598. [PubMed Link] | [ Full text ]
  • Bazan, VM ; Rodgers-Fischl, P ; Zwischenberger, JB "Supportive Therapy: Extracorporeal Membrane Oxygenation." Critical care clinics 36, 3 (2020): 517-529. [PubMed Link] | [ Full text ]
  • Turcios, L.; Marti, F.; Watt, DS ; Kril, LM ; Khurana, A.; Chapelin, F ; Liu, C.; Zwischenberger, JB ; Evers, BM ; Gedaly, R. "Mitochondrial uncoupling and the disruption of the metabolic network in hepatocellular carcinoma." Oncotarget 11, 31 (2020): 3013-3024. [PubMed Link] | [ Full text ]
  • Gleason, TG ; Argenziano, M.; Bavaria, JE ; Kane, LC ; Coselli, JS ; Engelman, RM ; Tanaka, KA ; Awad, A.; Sekela, ME ; Zwischenberger, JB "Hemoadsorption to Reduce Plasma-Free Hemoglobin During Cardiac Surgery: Results of REFRESH I Pilot Study." Seminars in thoracic and cardiovascular surgery 31, 4 (2019): 783-793. [PubMed Link] | [ Full text ]
  • Meyerson, SL ; Odell, DD ; Zwischenberger, JB ; Schuller, M ; Williams, RG ; Bohnen, JD ; Dunnington, GL ; Torbeck, L.; Mullen, JT ; Mandell, SP ; Choti, MA ; Foley, E.; Are, C.; Auyang, E.; Chipman, J.; Choi, J.; Meier, AH ; Smink, DS ; Terhune, KP ; Wise, PE ; Soper, N.; Lillemoe, K.; Fryer, JP ; George, BC ; Procedural Learning and Safety, Collaborative. "The effect of gender on operative autonomy in general surgery residents." Surgery 166, 5 (2019): 738-743. [PubMed Link] | [ Full text ]
  • Bender, EM ; Rizzo, MG ; Meyerson, SL ; Zwischenberger, JB "Surgeon as Programmer: Overcoming Obstacles to the Use of Modern Internet Technology for Cardiothoracic Surgery." The Annals of thoracic surgery 108, 5 (2019): 1551-1554. [PubMed Link] | [ Full text ]
  • Yanagida, R.; Seethamraju, H ; Davenport, DL ; Tribble, TA ; Zwischenberger, JB ; Hoopes, CW "Bridging to lung transplantation with double-lumen venovenous extracorporeal membrane oxygenation." The International journal of artificial organs 42, 11 (2019): 621-627. [PubMed Link] | [ Full text ]
  • Zhou, C.; Wang, D.; Condemi, F.; Zhao, G.; Topaz, S.; Ballard-Croft, C.; Zwischenberger, JB "AvalonElite Double Lumen Cannula for Total Cavopulmonary Assist in Failing Fontan Sheep Model with Valved Extracardiac Conduit." ASAIO journal (American Society for Artificial Internal Organs : 1992) 65, 4 (2019): 361-366. [PubMed Link] | [ Full text ]
  • Fryer, J.; Schuller, M ; Wnuk, G ; Meyerson, S ; Zwischenberger, J.; Meier, A.; Williams, R.; George, B. "Identifying and Addressing High Priority Issues in General Surgery Training and Education." Journal of surgical education 76, 1 (2019): 50-54. [PubMed Link] | [ Full text ]
  • Guglin, M.; Zucker, MJ ; Bazan, VM ; Bozkurt, B.; Banayosy, El ; Estep, JD ; Gurley, J.; Nelson, K.; Malyala, R ; Panjrath, GS ; Zwischenberger, JB ; Pinney, SP "Venoarterial ECMO for Adults: JACC Scientific Expert Panel." Journal of the American College of Cardiology 73, 6 (2019): 698-716. [PubMed Link] | [ Full text ]
  • Williams, RG ; George, BC ; Bohnen, JD ; Meyerson, SL ; Schuller, MC ; Meier, AH ; Torbeck, L.; Mandell, SP ; Mullen, JT ; Smink, DS ; Chipman, JG ; Auyang, ED ; Terhune, KP ; Wise, PE ; Choi, J.; Foley, EF ; Choti, MA ; Are, C.; Soper, N.; Zwischenberger, JB ; Dunnington, GL ; Lillemoe, KD ; Fryer, JP ; Procedural Learning and Safety, Collaborative. "Is the operative autonomy granted to a resident consistent with operative performance quality." Surgery 164, 3 (2018): 566-570. [PubMed Link] | [ Full text ]
  • Stride, HP ; George, BC ; Williams, RG ; Bohnen, JD ; Eaton, MJ ; Schuller, MC ; Zhao, L.; Yang, A.; Meyerson, SL ; Scully, R.; Dunnington, GL ; Torbeck, L.; Mullen, JT ; Mandell, SP ; Choti, M.; Foley, E.; Are, C.; Auyang, E.; Chipman, J.; Choi, J.; Meier, A.; Smink, D.; Terhune, KP ; Wise, P.; DaRosa, D.; Soper, N.; Zwischenberger, JB ; Lillemoe, K.; Fryer, JP "Relationship of procedural numbers with meaningful procedural autonomy in general surgery residents." Surgery 163, 3 (2018): 488-494. [PubMed Link] | [ Full text ]
  • Prager, RL ; Berlioz, Murillo ; Trachiotis, GD ; Zwischenberger, JB ; Sade, RM "Battling the Chimaera: How Much Disclosure of Rare Risks Is Necessary?" The Annals of thoracic surgery 106, 2 (2018): 327-332. [PubMed Link] | [ Full text ]
  • Hsu, PL ; Wang, D.; Ballard-Croft, C.; Xiao, D.; Zwischenberger, JB "A Numerical Simulation Comparing a Cavopulmonary Assist Device and VA ECMO for Failing Fontan Support." ASAIO journal (American Society for Artificial Internal Organs : 1992) 63, 5 (2017): 604-612. [PubMed Link] | [ Full text ]
  • Zhao, J.; Wang, D.; Ballard-Croft, C.; Wang, J.; Hsu, PL ; Bacchetta, M.; Zwischenberger, JB "Hybrid Extracorporeal Membrane Oxygenation Using Avalon Elite Double Lumen Cannula Ensures Adequate Heart/Brain Oxygen Supply." The Annals of thoracic surgery 104, 3 (2017): 847-853. [PubMed Link] | [ Full text ]
  • Meyerson, SL ; Sternbach, JM ; Zwischenberger, JB ; Bender, EM "Resident Autonomy in the Operating Room: Expectations Versus Reality." The Annals of thoracic surgery 104, 3 (2017): 1062-1068. [PubMed Link] | [ Full text ]
  • George, BC ; Bohnen, JD ; Williams, RG ; Meyerson, SL ; Schuller, MC ; Clark, MJ ; Meier, AH ; Torbeck, L.; Mandell, SP ; Mullen, JT ; Smink, DS ; Scully, RE ; Chipman, JG ; Auyang, ED ; Terhune, KP ; Wise, PE ; Choi, JN ; Foley, EF ; Dimick, JB ; Choti, MA ; Soper, NJ ; Lillemoe, KD ; Zwischenberger, JB ; Dunnington, GL ; DaRosa, DA ; Fryer, JP ; Procedural Learning and Safety Collaborative, (PLSC). "Readiness of US General Surgery Residents for Independent Practice." Annals of surgery 266, 4 (2017): 582-594. [PubMed Link] | [ Full text ]
  • Zwischenberger, JB ; Pitcher, HT "Extracorporeal Membrane Oxygenation Management: Techniques to Liberate from Extracorporeal Membrane Oxygenation and Manage Post-Intensive Care Unit Issues." Critical care clinics 33, 4 (2017): 843-853. [PubMed Link] | [ Full text ]
  • Jones-Akhtarekhavari, J.; Tribble, TA ; Zwischenberger, JB "Developing an Extracorporeal Membrane Oxygenation Program." Critical care clinics 33, 4 (2017): 767-775. [PubMed Link] | [ Full text ]
  • Meyerson, SL ; Sternbach, JM ; Zwischenberger, JB ; Bender, EM "The Effect of Gender on Resident Autonomy in the Operating room." Journal of surgical education 74, 6 (2017): e111-e118. [PubMed Link] | [ Full text ]
  • Karim, AS ; Sternbach, JM ; Bender, EM ; Zwischenberger, JB ; Meyerson, SL "Quality of Operative Performance Feedback Given to Thoracic Surgery Residents Using an App-Based System." Journal of surgical education 74, 6 (2017): e81-e87. [PubMed Link] | [ Full text ]
  • Trudzinski, FC ; Wilkens, H.; Moerer, O.; Muellenbach, RM ; Langer, F.; Hoopes, CW ; Zwischenberger, JB ; Lepper, PM "Lung Transplant Candidates on Extracorporeal Support." Chest 151, 5 (2017): 1177-1178. [PubMed Link] | [ Full text ]
  • Zhou, C.; Wang, D.; Ballard-Croft, C.; Zhao, G.; Reda, HK ; Topaz, S.; Zwischenberger, J. "A transapical-to-aorta double lumen cannula-based neonate left ventricular assist device efficiently unloads the left ventricle in neonate lambs." The Journal of thoracic and cardiovascular surgery 153, 1 (2017): 175-182. [PubMed Link] | [ Full text ]
  • Williams, RG ; George, BC ; Meyerson, SL ; Bohnen, JD ; Dunnington, GL ; Schuller, MC ; Torbeck, L.; Mullen, JT ; Auyang, E.; Chipman, JG ; Choi, J.; Choti, M.; Endean, E.; Foley, EF ; Mandell, S.; Meier, A.; Smink, DS ; Terhune, KP ; Wise, P.; DaRosa, D.; Soper, N.; Zwischenberger, JB ; Lillemoe, KD ; Fryer, JP ; Procedural Learning and Safety, Collaborative. "What factors influence attending surgeon decisions about resident autonomy in the operating room?" Surgery 162, 6 (2017): 1314-1319. [PubMed Link] | [ Full text ]
  • Bolanos, MD ; Zwischenberger, JB "Human factors and human nature in cardiothoracic surgery." Journal of thoracic disease 9, 8 (2017): 2268-2270. [PubMed Link] | [ Full text ]
  • Alexander, JV ; Grulke, EA ; Zwischenberger, JB "High Levels of Residue within Polymeric Hollow Fiber Membranes Used for Blood Oxygenation." ASAIO journal (American Society for Artificial Internal Organs : 1992) 62, 6 (2016): 690-696. [PubMed Link] | [ Full text ]
  • Bohnen, JD ; George, BC ; Williams, RG ; Schuller, MC ; DaRosa, DA ; Torbeck, L.; Mullen, JT ; Meyerson, SL ; Auyang, ED ; Chipman, JG ; Choi, JN ; Choti, MA ; Endean, ED ; Foley, EF ; Mandell, SP ; Meier, AH ; Smink, DS ; Terhune, KP ; Wise, PE ; Soper, NJ ; Zwischenberger, JB ; Lillemoe, KD ; Dunnington, GL ; Fryer, JP ; Procedural Learning and Safety Collaborative, (PLSC). "The Feasibility of Real-Time Intraoperative Performance Assessment With SIMPL (System for Improving and Measuring Procedural Learning): Early Experience From a Multi-institutional Trial." Journal of surgical education 73, 6 (2016): e118-e130. [PubMed Link] | [ Full text ]
  • Zwischenberger, BA ; Kister, N.; Zwischenberger, JB ; Martin, JT "Laparoscopic Robot-Assisted Diaphragm Plication." The Annals of thoracic surgery 101, 1 (2016): 369-71. [PubMed Link] | [ Full text ]
  • Martin, JT ; Durbin, EB ; Chen, L.; Gal, T.; Mahan, A.; Ferraris, V.; Zwischenberger, J. "Nodal Upstaging During Lung Cancer Resection Is Associated With Surgical Approach." The Annals of thoracic surgery 101, 1 (2016): 238-44; discussion 44-5. [PubMed Link] | [ Full text ]
  • Zwischenberger, BA ; Tzeng, CW ; Ward, ND ; Zwischenberger, JB ; Martin, JT "Venous Thromboembolism Prophylaxis For Esophagectomy: A Survey of Practice Patterns Among Thoracic Surgeons." The Annals of thoracic surgery 101, 2 (2016): 489-94. [PubMed Link] | [ Full text ]
  • Condemi, F.; Wang, D.; Fragomeni, G.; Yang, F.; Zhao, G.; Jones, C.; Ballard-Croft, C.; Zwischenberger, JB "Percutaneous Double Lumen Cannula for Right Ventricle Assist Device System: A Computational Fluid Dynamics Study." Biocybernetics and biomedical engineering 36, 3 (2016): 482-490. [PubMed Link] |
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