To the Bluegrass and Beyond: Alumnus John Charles Reflects on 30-year career at NASA

Why?That's the question John Charles constantly asked his parents as a boy. His father was a trained geologist, but he struggled to answer his son's barrage of questions about nature. So he made sure young...

Tags - Saha Cardiovascular Research Center, Cariovascular Research Day

Posted - Jan 17Read More

4th Annual Symposium "Healthy Hearts for Women"

Agenda8:30-9:00                    Breakfast9:00 - 9:05 Introduction (Dr. Arnett)9:05 - 9:30Dr. Donna Arnett(Dean’s Office, Dept. Public Heath, UK)9:30 - 10:20 Dr. Virginia Miller(Mayo Clinic)“Sex-specific...

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Posted - Jan 11Read More

"Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP"

Cholesterol homeostasis is maintained through concerted action of the SREBPs and LXRs. Here, we report that RNF145, a previously uncharacterized ER membrane ubiquitin ligase, participates in crosstalk between...

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Posted - Dec 7Read More

Gill Heart Institute Cardiovascular Research Day Highlights Innovations in Cardiovascular Health

More than 350 researchers, students and guests attended the 20th University of Kentucky Cardiovascular Research Day at the Lexington Convention Center, an annual event that celebrates the innovative research...

Tags - CVRC, Research

Posted - Nov 20Read More

"Calpain Inhibition Attenuates Adipose Tissue Inflammation and Fibrosis in Diet-induced Obese Mice"

Latha Muniappan1, Aida Javidan1, Weihua Jiang1, Shayan Mohammadmoradi 1, Jessica J.Moorleghen1, Wendy S. Katz1, Anju Balakrishnan1, Deborah A. Howatt1 & VenkateswaranSubramanian1,2Adipose tissue...

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Posted - Oct 31Read More

"Targeting hepatic heparin-binding EGF-like growth factor (HB-EGF) induces anti-hyperlipidemia leading to reduction of angiotensin II-induced aneurysm development"

OBJECTIVE:The upregulated expression of heparin binding EGF-like growth factor (HB-EGF) in the vessel and circulation is associated with risk of cardiovascular disease. In this study, we tested the effects of...

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Posted - Oct 19Read More

2017 Saha Awardees Announced

The Saha Cardiovascular Research Center recently announced the winners of the 2017 Saha Awards. These annual awards are given to Medical and Nursing students as well as to a nurse educator. The awards are...

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Posted - Oct 11Read More

"The dual role of group V secretory phospholipase A2 in pancreatic β-cells."

AbstractPURPOSE:Group X (GX) and group V (GV) secretory phospholipase A2 (sPLA2) potently release arachidonic acid (AA) from the plasma membrane of intact cells. We previously demonstrated that GX sPLA2...

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Posted - Sep 19Read More

Registration Open for the 2017 SELRC

 2017 South East Lipid Research ConferenceNovember 2-4, 2017 21C Museum Hotel Lexington, KY www.SELRC.orgSouth East Lipid Research Conference (SELRC) is scheduled in conjunction with Cardiovascular Research...

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Posted - Sep 8Read More

Registration Now Open for the 2017 Cardiovascular Research Day

  Registration is now open for the20th Annual University of KentuckyGill Heart InstituteCardiovascular Research Day Click Here to Register Download a Schedule of the Day Registration and Abstract Submission...

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Posted - Sep 8Read More

Saha Awards for Cardiovascular Research and Education

The Saha Cardiovascular Research Center is now accepting applications for the 2017 Saha Awards.The application process will close on Friday, September 15, 2017. The University of Kentucky Saha Cardiovascular...

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Posted - Aug 15Read More

Smooth Muscle Cells Derived From Second Heart Field and Cardiac Neural Crest Reside in Spatially Distinct Domains in the Media of the Ascending Aorta

Sawada H, Rateri DL, Moorleghen JJ, Majesky MW, Daugherty A.OBJECTIVE: Smooth muscle cells (SMCs) of the proximal thoracic aorta are embryonically derived from the second heart field (SHF) and cardiac neural...

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Posted - Jul 28Read More

A New Mouse Model for Introduction of Aortic Aneurysm by Implantation of Deoxycorticosterone Acetate Pellets or Aldosterone Infusion in the Presence of High Salt.

Dysfunction of the renin-angiotensin-aldosterone system (RAAS) has been implicated in the etiologies of many cardiovascular diseases, including aortic aneurysm. In particular, the infusion of angiotensin II (...

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Posted - Jun 7Read More

Save the Date - SELRC!

Click here to be directed to the 2017 SELRC

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Posted - May 16Read More

Stromp Receives Prestigious Summa Cum Laude Award at International Society for Magnetic Resonance in Medicine Conference

Tori Stromp, PhD, a recent graduate of the Department of Physiology and a member of the Saha Cardiovascular Research Center, recently received the prestigious Summa Cum Laude Award at the International Society...

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Posted - Apr 11Read More

Save The Date for Cardiovascular Research Day!

Click here to be directed to the 2017 Cardiovascular Research Day homepage

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Posted - Mar 21Read More