Faculty Publications - 2017

  • Kim, H.W.; Blomkalns, A.L.; Ogbi, M.; Thomas, M.; Gavrila, D.; Neltner, B.S.; Cassis, L.A.; Thompson, R.W.; Weiss, R.M.; Lindower, P.D.; Blanco, V.M.; McCormick, M.L.; Daugherty, A.; Fu, X.; Hazen, S.L.; Stansfield, B.K.; Huo, Y.; Fulton, D.J.R.; Chatterjee, T.; Weintraub, N.L. Role of myeloperoxidase in abdominal aortic aneurysm formation: mitigation by taurine. American journal of physiology. Heart and circulatory physiology 2017 ajpheart.00296.2017 [PubMed Link] | [Full Text]
  • Oben, K.Z.; Alhakeem, S.S.; McKenna, M.K.; Brandon, J.A.; Mani, R.; Noothi, S.K.; Jinpeng, L.; Akunuru, S.; Dhar, S.K.; Singh, I.P.; Liang, Y.; Wang, C.; Abdel-Latif, A.; Stills HF, J.; St Clair, D.K.; Geiger, H.; Muthusamy, N.; Tohyama, K.; Gupta, R.C.; Bondada, S. Oxidative stress-induced JNK/AP-1 signaling is a major pathway involved in selective apoptosis of myelodysplastic syndrome cells by Withaferin-A. Oncotarget 8 44 2017 77436-77452 [PubMed Link] | [Full Text]
  • Chandra, M.; Escalante-Alcalde, D.; Bhuiyan, M.S.; Orr, A.W.; Kevil, C.; Morris, A.J.; Nam, H.; Dominic, P.; McCarthy, K.J.; Miriyala, S.; Panchatcharam, M. Cardiac-specific inactivation of LPP3 in mice leads to myocardial dysfunction and heart failure. Redox biology 14 2017 261-271 [PubMed Link] | [Full Text]
  • Dong, A.; Mueller, P.; Yang, F.; Yang, L.; Morris, A.; Smyth, S.S. Direct thrombin inhibition with dabigatran attenuates pressure overload-induced cardiac fibrosis and dysfunction in mice. Thrombosis research 159 2017 58-64 [PubMed Link] | [Full Text]
  • Dong, A.; Mueller, P.; Yang, F.; Yang, L.; Morris, A.; Smyth, S.S. Direct thrombin inhibition with dabigatran attenuates pressure overload-induced cardiac fibrosis and dysfunction in mice. Thrombosis research 159 2017 58-64 [PubMed Link] | [Full Text]
  • Adamiak, M.; Chelvarajan, L.; Lynch, K.R.; Santos, W.L.; Abdel-Latif, A.; Ratajczak, M.Z. Mobilization studies in mice deficient in sphingosine kinase 2 support a crucial role of the plasma level of sphingosine-1-phosphate in the egress of hematopoietic stem progenitor cells. Oncotarget 8 39 2017 65588-65600 [PubMed Link] | [Full Text]
  • Sawada, H.; Rateri, D.L.; Moorleghen, J.J.; Majesky, M.W.; Daugherty, A. Smooth Muscle Cells Derived From Second Heart Field and Cardiac Neural Crest Reside in Spatially Distinct Domains in the Media of the Ascending Aorta-Brief Report. Arteriosclerosis, thrombosis, and vascular biology 37 9 2017 1722-1726 [PubMed Link] | [Full Text]
  • Muniappan, L.; Javidan, A.; Jiang, W.; Mohammadmoradi, S.; Moorleghen, J.J.; Katz, W.S.; Balakrishnan, A.; Howatt, D.A.; Subramanian, V. Calpain Inhibition Attenuates Adipose Tissue Inflammation and Fibrosis in Diet-induced Obese Mice. Scientific reports 7 1 2017 14398 [PubMed Link] | [Full Text]
  • Liu, D.J.; Peloso, G.M.; Yu, H.; Butterworth, A.S.; Wang, X.; Mahajan, A.; Saleheen, D.; Emdin, C.; Alam, D.; Alves, A.C.; Amouyel, P.; Di Angelantonio, E.; Arveiler, D.; Assimes, T.L.; Auer, P.L.; Baber, U.; Ballantyne, C.M.; Bang, L.E.; Benn, M.; Bis, J.C.; Boehnke, M.; Boerwinkle, E.; Bork-Jensen, J.; Bottinger, E.P.; Brandslund, I.; Brown, M.; Busonero, F.; Caulfield, M.J.; Chambers, J.C.; Chasman, D.I.; Chen, Y.E.; Chen, Y.I.; Chowdhury, R.; Christensen, C.; Chu, A.Y.; Connell, J.M.; Cucca, F.; Cupples, L.A.; Damrauer, S.M.; Davies, G.; Deary, I.J.; Dedoussis, G.; Denny, J.C.; Dominiczak, A.; Dubé, M.P.; Ebeling, T.; Eiriksdottir, G.; Esko, T.; Farmaki, A.E.; Feitosa, M.F.; Ferrario, M.; Ferrieres, J.; Ford, I.; Fornage, M.; Franks, P.W.; Frayling, T.M.; Frikke-Schmidt, R.; Fritsche, L.G.; Frossard, P.; Fuster, V.; Ganesh, S.K.; Gao, W.; Garcia, M.E.; Gieger, C.; Giulianini, F.; Goodarzi, M.O.; Grallert, H.; Grarup, N.; Groop, L.; Grove, M.L.; Gudnason, V.; Hansen, T.; Harris, T.B.; Hayward, C.; Hirschhorn, J.N.; Holmen, O.L.; Huffman, J.; Huo, Y.; Hveem, K.; Jabeen, S.; Jackson, A.U.; Jakobsdottir, J.; Jarvelin, M.R.; Jensen, G.B.; Jørgensen, M.E.; Jukema, J.W.; Justesen, J.M.; Kamstrup, P.R.; Kanoni, S.; Karpe, F.; Kee, F.; Khera, A.V.; Klarin, D.; Koistinen, H.A.; Kooner, J.S.; Kooperberg, C.; Kuulasmaa, K.; Kuusisto, J.; Laakso, M.; Lakka, T.; Langenberg, C.; Langsted, A.; Launer, L.J.; Lauritzen, T.; Liewald, D.C.M.; Lin, L.A.; Linneberg, A.; Loos, R.J.F.; Lu, Y.; Lu, X.; Mägi, R.; Malarstig, A.; Manichaikul, A.; Manning, A.K.; Mäntyselkä, P.; Marouli, E.; Masca, N.G.D.; Maschio, A.; Meigs, J.B.; Melander, O.; Metspalu, A.; Morris, A.P.; Morrison, A.C.; Mulas, A.; Müller-Nurasyid, M.; Munroe, P.B.; Neville, M.J.; Nielsen, J.B.; Nielsen, S.F.; Nordestgaard, B.G.; Ordovas, J.M.; Mehran, R.; O'Donnell, C.J.; Orho-Melander, M.; Molony, C.M.; Muntendam, P.; Padmanabhan, S.; Palmer, C.N.A.; Pasko, D.; Patel, A.P.; Pedersen, O.; Perola, M.; Peters, A.; Pisinger, C.; Pistis, G.; Polasek, O.; Poulter, N.; Psaty, B.M.; Rader, D.J.; Rasheed, A.; Rauramaa, R.; Reilly, D.F.; Reiner, A.P.; Renström, F.; Rich, S.S.; Ridker, P.M.; Rioux, J.D.; Robertson, N.R.; Roden, D.M.; Rotter, J.I.; Rudan, I.; Salomaa, V.; Samani, N.J.; Sanna, S.; Sattar, N.; Schmidt, E.M.; Scott, R.A.; Sever, P.; Sevilla, R.S.; Shaffer, C.M.; Sim, X.; Sivapalaratnam, S.; Small, K.S.; Smith, A.V.; Smith, B.H.; Somayajula, S.; Southam, L.; Spector, T.D.; Speliotes, E.K.; Starr, J.M.; Stirrups, K.E.; Stitziel, N.; Strauch, K.; Stringham, H.M.; Surendran, P.; Tada, H.; Tall, A.R.; Tang, H.; Tardif, J.C.; Taylor, K.D.; Trompet, S.; Tsao, P.S.; Tuomilehto, J.; Tybjaerg-Hansen, A.; Zuydam, N.R.; Varbo, A.; Varga, T.V.; Virtamo, J.; Waldenberger, M.; Wang, N.; Wareham, N.J.; Warren, H.R.; Weeke, P.E.; Weinstock, J.; Wessel, J.; Wilson, J.G.; Wilson, P.W.F.; Xu, M.; Yaghootkar, H.; Young, R.; Zeggini, E.; Zhang, H.; Zheng, N.S.; Zhang, W.; Zhang, Y.; Zhou, W.; Zhou, Y.; Zoledziewska, M.; Charge Diabetes Working, G.; EPIC-InterAct, C.; EPIC-CVD, C.; GOLD, C.; VA Million Veteran, P.; Howson, J.M.M.; Danesh, J.; McCarthy, M.I.; Cowan, C.A.; Abecasis, G.; Deloukas, P.; Musunuru, K.; Willer, C.J.; Kathiresan, S. Exome-wide association study of plasma lipids in >300,000 individuals. Nature genetics 2017 [PubMed Link] | [Full Text]
  • Butt, M.U.; Buzsaki, L.A.; Smyth, S.S.; Elayi, S.C. Deep Vein Thrombosis Complicated by Spontaneous Iliopsoas Hematoma in Patient with Septic Shock. The American journal of case reports 18 2017 1148-1152 [PubMed Link] | [Full Text]
  • Sheppard, M.B. Researcher, Heal Thyself? Circulation research 121 10 2017 1122-1123 [PubMed Link] | [Full Text]
  • Zhang, L.; Rajbhandari, P.; Priest, C.; Sandhu, J.; Wu, X.; Temel, R.; Castrillo, A.; Aguiar Vallim, T.Q.; Sallam, T.; Tontonoz, P. Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP. eLife 6 2017 [PubMed Link] | [Full Text]
  • Qing, H.; Jones, K.L.; Heywood, E.B.; Lu, H.; Daugherty, A.; Bruemmer, D. Deletion of the NR4A nuclear receptor NOR1 in hematopoietic stem cells reduces inflammation but not abdominal aortic aneurysm formation. BMC cardiovascular disorders 17 1 2017 271 [PubMed Link] | [Full Text]
  • Qing, H.; Jones, K.L.; Heywood, E.B.; Lu, H.; Daugherty, A.; Bruemmer, D. Deletion of the NR4A nuclear receptor NOR1 in hematopoietic stem cells reduces inflammation but not abdominal aortic aneurysm formation. BMC cardiovascular disorders 17 1 2017 271 [PubMed Link] | [Full Text]
  • Shridas, P.; Noffsinger, V.P.; Trumbauer, A.C.; Webb, N.R. The dual role of group V secretory phospholipase A<sub>2</sub> in pancreatic β-cells. Endocrine 58 1 2017 47-58 [PubMed Link] | [Full Text]
  • George, B.; Parazino, M.; Omar, H.R.; Davis, G.; Guglin, M.; Gurley, J.; Smyth, S. A retrospective comparison of survivors and non-survivors of massive pulmonary embolism receiving veno-arterial extracorporeal membrane oxygenation support. Resuscitation 122 2017 1-5 [PubMed Link] | [Full Text]
  • Alsiraj, Y.; Thatcher, S.E.; Blalock, E.; Fleenor, B.; Daugherty, A.; Cassis, L.A. Sex Chromosome Complement Defines Diffuse Versus Focal Angiotensin II-Induced Aortic Pathology. Arteriosclerosis, thrombosis, and vascular biology 2017 [PubMed Link] | [Full Text]
  • Ogunbayo, G.O.; Misumida, N.; Olorunfemi, O.; Elbadawi, A.; Saheed, D.; Messerli, A.; Elayi, C.S.; Smyth, S.S. Comparison of Outcomes in Patients Having Acute Myocardial Infarction With Versus Without Sickle-Cell Anemia. The American journal of cardiology 120 10 2017 1768-1771 [PubMed Link] | [Full Text]
  • Smetana, K.S.; Dunne, J.; Parrott, K.; Davis, G.A.; Collier, A.C.S.; Covell, M.; Smyth, S. Oral factor Xa inhibitors for the treatment of left ventricular thrombus: a case series. Journal of thrombosis and thrombolysis 44 4 2017 519-524 [PubMed Link] | [Full Text]
  • Howatt, D.A.; Dajee, M.; Xie, X.; Moorleghen, J.; Rateri, D.L.; Balakrishnan, A.; Da Cunha, V.; Johns, D.G.; Gutstein, D.E.; Daugherty, A.; Lu, H. Relaxin and Matrix Metalloproteinase-9 in Angiotensin II-Induced Abdominal Aortic Aneurysms. Circulation journal : official journal of the Japanese Circulation Society 81 6 2017 888-890 [PubMed Link] | [Full Text]
  • Daugherty, A. Recipients of the 2017 Early Career Investigator Awards. Arteriosclerosis, thrombosis, and vascular biology 37 5 2017 737 [PubMed Link] | [Full Text]
  • Brown, J.M.; Temel, R.E.; Graf, G.A. Para-bile-osis Establishes a Role for Nonbiliary Macrophage to Feces Reverse Cholesterol Transport. Arteriosclerosis, thrombosis, and vascular biology 37 5 2017 738-739 [PubMed Link] | [Full Text]
  • Keune, W.J.; Potjewyd, F.; Heidebrecht, T.; Salgado-Polo, F.; Macdonald, S.J.; Chelvarajan, L.; Abdel Latif, A.; Soman, S.; Morris, A.J.; Watson, A.J.; Jamieson, C.; Perrakis, A. Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators. Journal of medicinal chemistry 60 5 2017 2006-2017 [PubMed Link] | [Full Text]
  • Keune, W.J.; Potjewyd, F.; Heidebrecht, T.; Salgado-Polo, F.; Macdonald, S.J.; Chelvarajan, L.; Abdel Latif, A.; Soman, S.; Morris, A.J.; Watson, A.J.; Jamieson, C.; Perrakis, A. Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators. Journal of medicinal chemistry 60 5 2017 2006-2017 [PubMed Link] | [Full Text]
  • Hayek, S.S.; Klyachkin, Y.; Asfour, A.; Ghasemzadeh, N.; Awad, M.; Hesaroieh, I.; Ahmed, H.; Gray, B.; Kim, J.; Waller, E.K.; Quyyumi, A.A.; Abdel-Latif, A.K. Bioactive Lipids and Circulating Progenitor Cells in Patients with Cardiovascular Disease. Stem cells translational medicine 6 3 2017 731-735 [PubMed Link] | [Full Text]
  • Hager, M.R.; Narla, A.D.; Tannock, L.R. Dyslipidemia in patients with chronic kidney disease. Reviews in endocrine & metabolic disorders 18 1 2017 29-40 [PubMed Link] | [Full Text]
  • Ye, F.; Wang, J.A.; Daugherty, A.; Lu, H. Macrophage-mediated mechanisms in atherosclerosis: still tangled. Current opinion in lipidology 28 3 2017 286-287 [PubMed Link] | [Full Text]
  • Lu, H.; Daugherty, A. Aortic Aneurysms. Arteriosclerosis, thrombosis, and vascular biology 37 6 2017 e59-e65 [PubMed Link] | [Full Text]
  • Ye, F.; Wang, J.A.; Daugherty, A.; Lu, H. Macrophage-mediated mechanisms in atherosclerosis: still tangled. Current opinion in lipidology 28 3 2017 286-287 [PubMed Link] | [Full Text]
  • Lu, H.; Daugherty, A. Aortic Aneurysms. Arteriosclerosis, thrombosis, and vascular biology 37 6 2017 e59-e65 [PubMed Link] | [Full Text]
  • Misumida, N.; Kobayashi, A.; Kim, S.M.; Abdel-Latif, A.; Ziada, K.M. Role of Routine Follow-up Coronary Angiography After Percutaneous Coronary Intervention - Systematic Review and Meta-Analysis. Circulation journal : official journal of the Japanese Circulation Society 2017 [PubMed Link] | [Full Text]
  • Patil, V.S.; Gutierrez, A.M.; Sunkara, M.; Morris, A.J.; Hilt, J.Z.; Kalika, D.S.; Dziubla, T.D. Curcumin Acrylation for Biological and Environmental Applications. Journal of natural products 80 7 2017 1964-1971 [PubMed Link] | [Full Text]
  • Adamiak, M.; Chelvarajan, L.; Lynch, K.R.; Santos, W.L.; Abdel-Latif, A.; Ratajczak, M.Z. Mobilization studies in mice deficient in sphingosine kinase 2 support a crucial role of the plasma level of sphingosine-1-phosphate in the egress of hematopoietic stem progenitor cells. Oncotarget 2017 [PubMed Link] | [Full Text]
  • Ogunbayo, G.O.; Charnigo, R.; Darrat, Y.; Morales, G.; Kotter, J.; Olorunfemi, O.; Elbadawi, A.; Sorrell, V.L.; Smyth, S.S.; Elayi, C.S. Incidence, predictors, and outcomes associated with pneumothorax during cardiac electronic device implantation: A 16-year review in over 3.7 million patients. Heart rhythm 2017 [PubMed Link] | [Full Text]
  • Zhang, J.; Hughes, R.R.; Saunders, M.A.; Elshahawi, S.I.; Ponomareva, L.V.; Zhang, Y.; Winchester, S.R.; Scott, S.A.; Sunkara, M.; Morris, A.J.; Prendergast, M.A.; Shaaban, K.A.; Thorson, J.S. Identification of Neuroprotective Spoxazomicin and Oxachelin Glycosides via Chemoenzymatic Glycosyl-Scanning. Journal of natural products 80 1 2017 12-18 [PubMed Link] | [Full Text]
  • Daugherty, A.; Chen, Z.; Sawada, H.; Rateri, D.L.; Sheppard, M.B. Transforming Growth Factor-β in Thoracic Aortic Aneurysms: Good, Bad, or Irrelevant? Journal of the American Heart Association 6 1 2017 [PubMed Link] | [Full Text]
  • Alsiraj, Y.; Thatcher, S.E.; Charnigo, R.; Chen, K.; Blalock, E.; Daugherty, A.; Cassis, L.A. Female Mice With an XY Sex Chromosome Complement Develop Severe Angiotensin II-Induced Abdominal Aortic Aneurysms. Circulation 135 4 2017 379-391 [PubMed Link] | [Full Text]
  • Daugherty, A.; Chen, Z.; Sawada, H.; Rateri, D.L.; Sheppard, M.B. Transforming Growth Factor-β in Thoracic Aortic Aneurysms: Good, Bad, or Irrelevant? Journal of the American Heart Association 6 1 2017 [PubMed Link] | [Full Text]
  • Quyyumi, A.A.; Vasquez, A.; Kereiakes, D.J.; Klapholz, M.; Schaer, G.L.; Abdel-Latif, A.; Frohwein, S.; Henry, T.D.; Schatz, R.A.; Dib, N.; Toma, C.; Davidson, C.J.; Barsness, G.W.; Shavelle, D.M.; Cohen, M.; Poole, J.; Moss, T.; Hyde, P.; Kanakaraj, A.M.; Druker, V.; Chung, A.; Junge, C.; Preti, R.A.; Smith, R.L.; Mazzo, D.J.; Pecora, A.; Losordo, D.W. PreSERVE-AMI: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of Intracoronary Administration of Autologous CD34+ Cells in Patients With Left Ventricular Dysfunction Post STEMI. Circulation research 120 2 2017 324-331 [PubMed Link] | [Full Text]
  • Cavalcanti, R.; Aboul-Hosn, N.; Morales, G.; Abdel-Latif, A. Implantable Cardioverter Defibrillator for the Primary Prevention of Sudden Cardiac Death in Patients With Nonischemic Cardiomyopathy. Angiology 2017 3319717710851 [PubMed Link] | [Full Text]
  • Misumida, N.; Ogunbayo, G.O.; Kim, S.M.; Olorunfemi, O.; Elbadawi, A.; Charnigo, R.J.; Abdel-Latif, A.; Ziada, K.M. Higher Risk of Bleeding in Asians Presenting With ST-Segment Elevation Myocardial Infarction: Analysis of the National Inpatient Sample Database. Angiology 2017 3319717730168 [PubMed Link] | [Full Text]
  • Misumida, N.; Ogunbayo, G.O.; Kim, S.M.; Abdel-Latif, A.; Ziada, K.M. Higher Risk of Bleeding in Asians Presenting With Non-ST-Segment Elevation Myocardial Infarction. Angiology 2017 3319717736609 [PubMed Link] | [Full Text]
  • Adamiak, M.; Abdelbaset-Ismail, A.; Suszynska, M.; Abdel-Latif, A.; Ratajczak, J.; Ratajczak, M.Z. Novel evidence that the mannan-binding lectin pathway of complement activation plays a pivotal role in triggering mobilization of hematopoietic stem/progenitor cells by activation of both the complement and coagulation cascades. Leukemia 31 1 2017 262-265 [PubMed Link] | [Full Text]
  • Pumphrey, A.L.; Ye, S.; Yang, Z.; Simkin, J.; Gensel, J.C.; Abdel-Latif, A.; Vandsburger, M.H. Cardiac Chemical Exchange Saturation Transfer MR Imaging Tracking of Cell Survival or Rejection in Mouse Models of Cell Therapy. Radiology 282 1 2017 131-138 [PubMed Link] | [Full Text]
  • Wang, C.; Chen, H.; Zhu, W.; Xu, Y.; Liu, M.; Zhu, L.; Yang, F.; Zhang, L.; Liu, X.; Zhong, Z.; Zhao, J.; Jiang, J.; Xiang, M.; Yu, H.; Hu, X.; Lu, H.; Wang, J. Nicotine Accelerates Atherosclerosis in Apolipoprotein E-Deficient Mice by Activating α7 Nicotinic Acetylcholine Receptor on Mast Cells. Arteriosclerosis, thrombosis, and vascular biology 37 1 2017 53-65 [PubMed Link] | [Full Text]