Faculty Publications 2020

  • Naguib, YW ; Yu, Y.; Wei, SG ; Morris, A.; Givens, BE ; Mekkawy, AI ; Weiss, RM ; Felder, RB ; Salem, AK An Injectable Microparticle Formulation Provides Long-Term Inhibition of Hypothalamic ERK1/2 Activity and Sympathetic Excitation in Rats with Heart Failure. Molecular pharmaceutics 17 9 2020 3643-3648 [PubMed Link] | [Full Text]
  • Sreejit, G ; Abdel Latif, A.; Murphy, AJ ; Nagareddy, PR Emerging roles of neutrophil-borne S100A8/A9 in cardiovascular inflammation. Pharmacological research 161 2020 105212 [PubMed Link] | [Full Text]
  • Wu, CH ; Wu, C.; Howatt, DA ; Moorleghen, JJ ; Cassis, LA ; Daugherty, A.; Lu, HS Two Amino Acids Proximate to the Renin Cleavage Site of Human Angiotensinogen Do Not Affect Blood Pressure and Atherosclerosis in Mice-Brief Report. Arteriosclerosis, thrombosis, and vascular biology 40 9 2020 2108-2113 [PubMed Link] | [Full Text]
  • Bhalla, V ; Lamping, OF ; Abdel-Latif, A.; Bhalla, M ; Ziada, K.; Smyth, SS Contemporary Meta-Analysis of Extended Direct-Acting Oral Anticoagulant Thromboprophylaxis to Prevent Venous Thromboembolism. The American journal of medicine 133 9 2020 1074-1081.e8 [PubMed Link] | [Full Text]
  • Wu, CH ; Wu, C.; Howatt, DA ; Moorleghen, JJ ; Cassis, LA ; Daugherty, A.; Lu, HS Two Amino Acids Proximate to the Renin Cleavage Site of Human Angiotensinogen Do Not Affect Blood Pressure and Atherosclerosis in Mice-Brief Report. Arteriosclerosis, thrombosis, and vascular biology 40 9 2020 2108-2113 [PubMed Link] | [Full Text]
  • Bhalla, V ; Lamping, OF ; Abdel-Latif, A.; Bhalla, M ; Ziada, K.; Smyth, SS Contemporary Meta-Analysis of Extended Direct-Acting Oral Anticoagulant Thromboprophylaxis to Prevent Venous Thromboembolism. The American journal of medicine 133 9 2020 1074-1081.e8 [PubMed Link] | [Full Text]
  • Li, J.; Gupta, V.; Smyth, SS ; Cowley, A ; Du, G.; Sirrine, M ; Stearley, S ; Chadha, R.; Bhalla, V ; Williams, MV Value-based syncope evaluation and management: Perspectives of health care professionals on readiness, barriers and enablers. The American journal of emergency medicine 38 9 2020 1867-1874 [PubMed Link] | [Full Text]
  • Li, X.; Li, Z.; Zhou, H.; Gaynor, SM ; Liu, Y.; Chen, H.; Sun, R.; Dey, R.; Arnett, DK ; Aslibekyan, S.; Ballantyne, CM ; Bielak, LF ; Blangero, J.; Boerwinkle, E.; Bowden, DW ; Broome, JG ; Conomos, MP ; Correa, A.; Cupples, LA ; Curran, JE ; Freedman, BI ; Guo, X.; Hindy, G ; Irvin, MR ; Kardia, SLR ; Kathiresan, S.; Khan, AT ; Kooperberg, CL ; Laurie, CC ; Liu, XS ; Mahaney, MC ; Manichaikul, AW ; Martin, LW ; Mathias, RA ; McGarvey, ST ; Mitchell, BD ; Montasser, ME ; Moore, JE ; Morrison, AC ; O'Connell, JR ; Palmer, ND ; Pampana, A ; Peralta, JM ; Peyser, PA ; Psaty, BM ; Redline, S.; Rice, KM ; Rich, SS ; Smith, JA ; Tiwari, HK ; Tsai, MY ; Vasan, RS ; Wang, FF ; Weeks, DE ; Weng, Z.; Wilson, JG ; Yanek, LR ; TOPMed), Consortium. N.H.L.B.I.Tran; Working, Group. T.O.P.Med Lip; Neale, BM ; , ; Abecasis, GR ; Rotter, JI ; Willer, CJ ; Peloso, GM ; Natarajan, P ; Lin, X. Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. Nature genetics 52 9 2020 969-983 [PubMed Link] | [Full Text]
  • Smyth, SS ; Moliterno, D.; McClure, R.; Campbell, J.; Buckler, L ; McMullen, CA ; Whayne, TF ; Endean, E.; Sekela, M.; Karpf, M. Securing the Future for a Major Academic Cardiovascular Program: Hardwiring a Referral Network and Preparing for a Transition to Value-Based Reimbursement. Hospital topics 98 4 2020 163-171 [PubMed Link] |
  • Li, Y.; Ren, P.; Dawson, A.; Vasquez, HG ; Ageedi, W ; Zhang, C.; Luo, W.; Chen, R.; Li, Y.; Kim, S.; Lu, HS ; Cassis, LA ; Coselli, JS ; Daugherty, A.; Shen, YH ; Lemaire, SA Single-Cell Transcriptome Analysis Reveals Dynamic Cell Populations and Differential Gene Expression Patterns in Control and Aneurysmal Human Aortic Tissue. Circulation 142 14 2020 1374-1388 [PubMed Link] | [Full Text]
  • Al-Darraji, A.; Donahue, RR ; Tripathi, H.; Peng, H.; Levitan, BM ; Chelvarajan, L.; Haydar, D.; Gao, E.; Henson, D.; Gensel, JC ; Feola, DJ ; Venditto, VJ ; Abdel-Latif, A. Liposomal delivery of azithromycin enhances its immunotherapeutic efficacy and reduces toxicity in myocardial infarction. Scientific reports 10 1 2020 16596 [PubMed Link] | [Full Text]
  • Li, Y.; Ren, P.; Dawson, A.; Vasquez, HG ; Ageedi, W ; Zhang, C.; Luo, W.; Chen, R.; Li, Y.; Kim, S.; Lu, HS ; Cassis, LA ; Coselli, JS ; Daugherty, A.; Shen, YH ; Lemaire, SA Single-Cell Transcriptome Analysis Reveals Dynamic Cell Populations and Differential Gene Expression Patterns in Control and Aneurysmal Human Aortic Tissue. Circulation 142 14 2020 1374-1388 [PubMed Link] | [Full Text]
  • Deng, P.; Wang, C.; Wahlang, B.; Sexton, T.; Morris, AJ ; Hennig, B. Co-exposure to PCB126 and PFOS increases biomarkers associated with cardiovascular disease risk and liver injury in mice. Toxicology and applied pharmacology 409 2020 115301 [PubMed Link] | [Full Text]
  • Tripathi, H.; Al-Darraji, A.; Abo-Aly, M ; Peng, H.; Shokri, E ; Chelvarajan, L.; Donahue, R R.; Levitan, BM ; Gao, E.; Hernández, G.; Morris, AJ ; Smyth, SS ; Abdel-Latif, A. Autotaxin inhibition reduces cardiac inflammation and mitigates adverse cardiac remodeling after myocardial infarction. Journal of molecular and cellular cardiology 149 2020 95-114 [PubMed Link] | [Full Text]
  • Tripathi, H.; Al-Darraji, A.; Abo-Aly, M ; Peng, H.; Shokri, E ; Chelvarajan, L.; Donahue, R R.; Levitan, BM ; Gao, E.; Hernández, G.; Morris, AJ ; Smyth, SS ; Abdel-Latif, A. Autotaxin inhibition reduces cardiac inflammation and mitigates adverse cardiac remodeling after myocardial infarction. Journal of molecular and cellular cardiology 149 2020 95-114 [PubMed Link] | [Full Text]
  • Alsiraj, Y.; Thatcher, SE ; Blalock, E.; Saintilnord, WN ; Daugherty, A.; Lu, HS ; Luo, W.; Shen, YH ; Lemaire, SA ; Arnold, AP ; Cassis, LA Monosomy X in Female Mice Influences the Regional Formation and Augments the Severity of Angiotensin II-Induced Aortopathies. Arteriosclerosis, thrombosis, and vascular biology 2020 ATVBAHA120314407 [PubMed Link] | [Full Text]
  • Alsiraj, Y.; Thatcher, SE ; Blalock, E.; Saintilnord, WN ; Daugherty, A.; Lu, HS ; Luo, W.; Shen, YH ; Lemaire, SA ; Arnold, AP ; Cassis, LA Monosomy X in Female Mice Influences the Regional Formation and Augments the Severity of Angiotensin II-Induced Aortopathies. Arteriosclerosis, thrombosis, and vascular biology 2020 ATVBAHA120314407 [PubMed Link] | [Full Text]
  • Wu, C.; Ye, D.; Mullick, AE ; Li, Z.; Danser, AHJ ; Daugherty, A.; Lu, HS Effects of Renin-Angiotensin Inhibition on ACE2 (Angiotensin-Converting Enzyme 2) and TMPRSS2 (Transmembrane Protease Serine 2) Expression: Insights Into COVID-19. Hypertension (Dallas, Tex. : 1979) 76 4 2020 e29-e30 [PubMed Link] | [Full Text]
  • Sawada, H.; Franklin, MK ; Moorleghen, JJ ; Howatt, DA ; Kukida, M ; Lu, HS ; Daugherty, A. Ultrasound Monitoring of Descending Aortic Aneurysms and Dissections in Mice. Arteriosclerosis, thrombosis, and vascular biology 40 10 2020 2557-2559 [PubMed Link] | [Full Text]
  • Mohammadmoradi, S.; Howatt, DA ; Lu, HS ; Daugherty, A.; Saha, SP Bitter Melon (<i>Momordica charantia</i> L.) Supplementation Has No Effect on Hypercholesterolemia and Atherosclerosis in Mice. Current developments in nutrition 4 10 2020 nzaa148 [PubMed Link] |
  • Adamiak, M.; Abdel-Latif, A.; Bujko, K.; Thapa, A ; Anusz, K ; Tracz, M ; Brzezniakiewicz-Janus, K ; Ratajczak, J.; Kucia, M.; Ratajczak, MZ Nlrp3 Inflammasome Signaling Regulates the Homing and Engraftment of Hematopoietic Stem Cells (HSPCs) by Enhancing Incorporation of CXCR4 Receptor into Membrane Lipid Rafts. Stem cell reviews and reports 16 5 2020 954-967 [PubMed Link] | [Full Text]
  • Sawada, H.; Franklin, MK ; Moorleghen, JJ ; Howatt, DA ; Kukida, M ; Lu, HS ; Daugherty, A. Ultrasound Monitoring of Descending Aortic Aneurysms and Dissections in Mice. Arteriosclerosis, thrombosis, and vascular biology 40 10 2020 2557-2559 [PubMed Link] | [Full Text]
  • Wu, C.; Ye, D.; Mullick, AE ; Li, Z.; Danser, AHJ ; Daugherty, A.; Lu, HS Effects of Renin-Angiotensin Inhibition on ACE2 (Angiotensin-Converting Enzyme 2) and TMPRSS2 (Transmembrane Protease Serine 2) Expression: Insights Into COVID-19. Hypertension (Dallas, Tex. : 1979) 76 4 2020 e29-e30 [PubMed Link] | [Full Text]
  • Mohammadmoradi, S.; Howatt, DA ; Lu, HS ; Daugherty, A.; Saha, SP Bitter Melon (<i>Momordica charantia</i> L.) Supplementation Has No Effect on Hypercholesterolemia and Atherosclerosis in Mice. Current developments in nutrition 4 10 2020 nzaa148 [PubMed Link] |
  • Ge, Y.; Antiochos, P ; Steel, K ; Bingham, S ; Abdullah, S ; Chen, YY ; , ; Arai, AE ; Bandettini, WP ; Shanbhag, SM ; Patel, AR ; Farzaneh-Far, A ; Heitner, JF ; Shenoy, C ; Leung, SW ; González, JA ; Shah, DJ ; Raman, SV ; Ferrari, VA ; Schulz-Menger, J.; Stuber, M ; Simonetti, OP ; Kwong, RY Prognostic Value of Stress CMR Perfusion Imaging in Patients With Reduced Left Ventricular Function. JACC. Cardiovascular imaging 13 10 2020 2132-2145 [PubMed Link] | [Full Text]
  • Wu, C.; Ye, D.; Mullick, AE ; Li, Z.; Danser, AHJ ; Daugherty, A.; Lu, HS Effects of Renin-Angiotensin Inhibition on ACE2 (Angiotensin-Converting Enzyme 2) and TMPRSS2 (Transmembrane Protease Serine 2) Expression: Insights Into COVID-19. Hypertension (Dallas, Tex. : 1979) 76 4 2020 e29-e30 [PubMed Link] | [Full Text]
  • Ge, Y.; Steel, K ; Antiochos, P ; Bingham, S ; Abdullah, S ; , ; Arai, AE ; Bandettini, WP ; Shanbhag, SM ; Patel, AR ; Farzaneh-Far, A ; Heitner, JF ; Shenoy, C ; Leung, SW ; González, JA ; Shah, DJ ; Raman, SV ; Nawaz, H ; Ferrari, VA ; Schulz-Menger, J.; Stuber, M ; Simonetti, OP ; Kwong, RY Stress CMR in patients with obesity: insights from the Stress CMR Perfusion Imaging in the United States (SPINS) registry. European heart journal cardiovascular Imaging 2020 [PubMed Link] | [Full Text]
  • Leung, SW Are there ethnic differences in coronary volume and myocardial mass? If so, what does it mean? Journal of cardiovascular computed tomography 2020 [PubMed Link] | [Full Text]
  • Abo-Aly, M ; George, B.; Shokri, E ; Chelvarajan, L.; El-Helw, M ; Smyth, SS ; Abdel-Latif, A.; Ziada, K. Cangrelor in addition to standard therapy reduces cardiac damage and inflammatory markers in patients with ST-segment elevation myocardial infarction. Journal of thrombosis and thrombolysis 2020 [PubMed Link] | [Full Text]
  • Abo-Aly, M ; George, B.; Shokri, E ; Chelvarajan, L.; El-Helw, M ; Smyth, SS ; Abdel-Latif, A.; Ziada, K. Cangrelor in addition to standard therapy reduces cardiac damage and inflammatory markers in patients with ST-segment elevation myocardial infarction. Journal of thrombosis and thrombolysis 2020 [PubMed Link] | [Full Text]
  • Okuyama, M.; Jiang, W.; Javidan, A.; Chen, JZ ; Howatt, DA ; Yang, L.; Hamaguchi, M.; Yasugi, T ; Aono, J.; Vazquez-Padron, RI ; Subramanian, V. Lysyl Oxidase Inhibition Ablates Sexual Dimorphism of Abdominal Aortic Aneurysm Formation in Mice. Circulation 142 20 2020 1993-1995 [PubMed Link] | [Full Text]
  • Otaka, N ; Uchida, HA ; Okuyama, M.; Hada, Y ; Onishi, Y ; Kakio, Y.; Takeuchi, H.; Umebayashi, R.; Tanabe, K.; Subramanian, V.; Daugherty, A.; Sato, Y.; Wada, J. Vasohibin-2 Aggravates Development of Ascending Aortic Aneurysms But Not Abdominal Aortic Aneurysms Nor Atherosclerosis in ApoE Deficient Mice. American journal of hypertension 2020 [PubMed Link] | [Full Text]
  • Xiang, B.; Zhang, G.; Zhang, Y.; Wu, C.; Joshi, S.; Morris, AJ ; Ware, J.; Smyth, SS ; Whiteheart, SW ; Li, Z. Calcium Ion Chelation Preserves Platelet Function During Cold Storage. Arteriosclerosis, thrombosis, and vascular biology 2020 ATVBAHA120314879 [PubMed Link] | [Full Text]
  • Xiang, B.; Zhang, G.; Zhang, Y.; Wu, C.; Joshi, S.; Morris, AJ ; Ware, J.; Smyth, SS ; Whiteheart, SW ; Li, Z. Calcium Ion Chelation Preserves Platelet Function During Cold Storage. Arteriosclerosis, thrombosis, and vascular biology 2020 ATVBAHA120314879 [PubMed Link] | [Full Text]
  • Otaka, N ; Uchida, HA ; Okuyama, M.; Hada, Y ; Onishi, Y ; Kakio, Y.; Takeuchi, H.; Umebayashi, R.; Tanabe, K.; Subramanian, V.; Daugherty, A.; Sato, Y.; Wada, J. Vasohibin-2 Aggravates Development of Ascending Aortic Aneurysms But Not Abdominal Aortic Aneurysms Nor Atherosclerosis in ApoE Deficient Mice. American journal of hypertension 2020 [PubMed Link] | [Full Text]
  • Xiang, B.; Zhang, G.; Zhang, Y.; Wu, C.; Joshi, S.; Morris, AJ ; Ware, J.; Smyth, SS ; Whiteheart, SW ; Li, Z. Calcium Ion Chelation Preserves Platelet Function During Cold Storage. Arteriosclerosis, thrombosis, and vascular biology 2020 ATVBAHA120314879 [PubMed Link] | [Full Text]
  • Nagareddy, PR ; Sreejit, G ; Abo-Aly, M ; Jaggers, RM ; Chelvarajan, L.; Johnson, J.; Pernes, G ; Athmanathan, B ; Abdel-Latif, A.; Murphy, AJ NETosis Is Required for S100A8/A9-Induced Granulopoiesis After Myocardial Infarction. Arteriosclerosis, thrombosis, and vascular biology 40 11 2020 2805-2807 [PubMed Link] | [Full Text]
  • Thalman, C.; Horta, G.; Qiao, L.; Endle, H.; Tegeder, I.; Cheng, H.; Laube, G.; Sigurdsson, T ; Hauser, MJ ; Tenzer, S.; Distler, U.; Aoki, J.; Morris, AJ ; Geisslinger, G.; Röper, J.; Kirischuk, S.; Luhmann, HJ ; Radyushkin, K.; Nitsch, R.; Vogt, J. Correction: Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders. Molecular psychiatry 25 11 2020 3108 [PubMed Link] | [Full Text]
  • Smyth, S.; Gupta, V.; Williams, M.; Cowley, A ; Sirrine, M ; Surratt, H ; Chadha, R.; Stearley, S ; Bhalla, V ; Li, J. Identifying Guideline-Practice Gaps to Optimize Evaluation and Management for Patients With Syncope. The Canadian journal of cardiology 2020 [PubMed Link] | [Full Text]
  • Wu, PJ ; Peng, H.; Li, C.; Abdel-Latif, A.; Berron, BJ Adhesive stem cell coatings for enhanced retention in the heart tissue. ACS applied bio materials 3 5 2020 2930-2939 [PubMed Link] |
  • Mottaleb, MA ; Petriello, MC ; Morris, AJ High-Throughput UHPLC-MS/MS Measurement of Per- and Poly-Fluorinated Alkyl Substances in Human Serum. Journal of analytical toxicology 44 4 2020 339-347 [PubMed Link] | [Full Text]
  • Finlin, BS ; Memetimin, H ; Zhu, B.; Confides, AL ; Vekaria, HJ ; Khouli, RH El; Johnson, ZR ; Westgate, PM ; Chen, J.; Morris, AJ ; Sullivan, PG ; Dupont-Versteegden, EE ; Kern, PA The β3-adrenergic receptor agonist mirabegron improves glucose homeostasis in obese humans. The Journal of clinical investigation 130 5 2020 2319-2331 [PubMed Link] | [Full Text]
  • Daugherty, A. Recipients of the 2020 Early Career Investigator Awards. Arteriosclerosis, thrombosis, and vascular biology 40 5 2020 1017 [PubMed Link] | [Full Text]
  • Kim, S.; Subramanian, V.; Abdel-Latif, A.; Lee, S. Role of Heparin-Binding Epidermal Growth Factor-Like Growth Factor in Oxidative Stress-Associated Metabolic Diseases. Metabolic syndrome and related disorders 18 4 2020 186-196 [PubMed Link] |
  • Wayne, NB ; Davis, GA ; Macaulay, TE ; Beavers, CJ ; Messerli, AW ; Dugan, A.; Smyth, SS Reduced dose thrombolysis with ultrasound-facilitated catheter-directed administration for acute pulmonary embolism reduces length of stay. Journal of thrombosis and thrombolysis 49 4 2020 540-544 [PubMed Link] | [Full Text]