Clinical Scholars in Cardiovascular Science (T32HL091812)

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NOTE: This training program has available slots for Post-Doctoral Scholars. Interested individuals should contact Dr. Smyth as soon as possible to be considered, as directed by the instructions found at the bottom of this page.

Program Director: Susan Smyth, M.D., Ph.D.

Program Co-Director: Leigh Ann Callahan, M.D.

Description The University of Kentucky Training Program for Clinical Scholars in Cardiovascular Science is designed to prepare exceptional clinical and postdoctoral fellows to assume leadership positions directing multidisciplinary research in the field of cardiovascular medicine. In the last several years, as a consequence of substantial institutional commitment, we have assembled an integrated approach of incorporating basic, translational and clinical cardiovascular science in four concentrations: Thrombosis and Inflammation; Atherosclerosis and Aneurysm; Cardiac Hypertrophy and Heart Failure; and Vascular Cell Response to Stress. Our cardiovascular science strengths to provide a unique multidisciplinary training program that unites trainees across the disciplines of Medicine, Nursing, and Pharmacy with the goal of increasing the pipeline of clinical investigators who will bridge the gap between basic science advances and their application to clinical medicine. Specifically, we aim to:

1) To provide a rigorous and solid research education in the basic sciences related to cardiovascular research
2) To prepare new researchers for translational and clinical science in a highly interdisciplinary environment
3) To provide training in the efficient and ethical conduct of high quality laboratory management and science
4) To create an environment that incubates fellows and mentors with an innovative and nurturing structure of interlaced mentoring teams

The program is available to M.D., R.N./Ph.D., Pharm.D., and Ph.D.s with clinical emphasis who are at the early post-doctoral stage of their careers. Upon completion of the program, we anticipate that the trainees will have the experience and capabilities necessary to initiate an independent career as clinical investigator.


Training Faculty All training faculty are members of the Cardiovascular Research Center and are NIH-funded basic scientists and/or NIH- and industry-sponsored clinical scientists with primary research in one of four strength areas: Thrombosis, Heart Failure, Atherosclerosis and Aneurysm, and Vascular Biology. Across these four areas, the faculty share an interest in understanding at a cell and molecular level nodal check points in which inflammation, thrombosis, nutritional, and metabolic pathways intersect to impact the development and progression of ischemic vascular disease, aortic aneurysm, and heart failure.

20 scholars supported to date

3 still in training

  •  >100 publications
  • >70% with faculty appointments in academics, all except one with external funding subsequent to T32 training
  • Over 20 external grants, including K01s, K08s, K99/R00s, multiple R01, and U01 for implementation science
  • 1 senior scientists within VA research system
  • 3 in industry
 



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